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KMID : 0854720110310040237
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Korean Journal of Asthma, Allergy and Clinical Immunology
2011 Volume.31 No. 4 p.237 ~ p.345
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Eosinophilia
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Choi Dong-Chull
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Abstract
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Blood eosinophilia can be induced by either the cytokine-mediated reactive phenomenon (secondary) or the integral
phenotype of an underlying hematological neoplasm(primary). Secondary eosinophilia is usually associated with
parasitosis in underdeveloped countries or allergic diseases in developed countries. Initial approaches should focus on
excluding possible causes of secondary eosinophilia, including helminthic parasite infections, undiagnosed allergic diseases, varied types of adverse drug reactions, and other eosinophil-associated syndromes, such as eosinophilic gastroenteritis and eosinophilic lung diseases. If secondary eosinophilia is excluded, attention must be directed to considerations of varied other forms of primary eosinophilia. Primary eosinophilia can be classified as clonal or idiopathic
depending on the presence or absence of molecular, cytogenetic or histological evidence for myeloid malignancy. This
article presents a comprehensive review of both secondary and primary eosinophilic disorders with some author’s clinical
experience with hypereosinophilia.
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KEYWORD
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Primrary eosinophilia, Secondary eosinophilia
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